The nature of human suffering is addressed in the myth of Genesis.
Human beings, through exercise of their free will estranged themselves from God. Instead of God rescinding the life of humanity completely for this disobedience, he allowed humanity to live on. The consequences of our chosen estrangemeant from God brought upon for human beings a change/corruption in our physical and spiritual nature. We will evil (sin) and we suffer physically. We pass this nature on.
God did not abandon us, though. He respected out choice by allowing us to live with it. And providied hope. Instead of naturally obtaining spiritual and physical health, we must work for it by employing reason and our faith in God.
He also promised redemption and reconciliation according to his plan.
Humanity's first sin was that of pride and turning from God in that we desired to set ourself up as our own gods. The life of Christ and his death/ressurection is God's answer. Humanity could not raise themselves to the level of God, but God can lower himself to the level of humanity. This act of divine humility is manifested in the life of Christ, born in a humble manger to a poor family in the poltical backwater of the great Roman Empire, Christ humbled himself utterly in his life allowing human beings to have utter power and control over him--turning the tables so to speak--giving humans what they want -power over God--but then using that as a means to saving them. Thus his human life becomes the ultimate example of humility, the virtue that answers the first estranging sin.
We still live with the effects of that sin-for now. We can choose to either worship God or ourselves. We suffer, but the answer and reponse that Christ gives is that suffering is temporary and that someday we will regain what we threw away. Does it make suffering in the moment easier? Well, yes and no. Christ in the garden, fully human and fully God, shows us that God understands how difficult the road we chose is on us, but offers us hope.
Believe it or don't believe it, but I for one do not think of it as some simple comic book plot. I think of it as a narrative that all can grasp regardless of education, background, or native intelligence. It is a story accessible to all because it is for all.
Sorry, if there are typos, but I am writing this on the fly on my phone and without my glasses.