Nuclear weapons in Iran
Undesirable, but not a direct danger to us. We can let our little proxy over in the ME deal with that. We could remove most of the affect that would have on us - which would be the affect on oil - by making ourselves energy independent. We should be pursuing renewables with a vengeance, but also speculating for oil in other areas we have closed off as options, currently. But we aren't. Are you so naive as to believe that is not due to lobbying from special interests paralyzing the process? On both sides of the aisle?
Russia taking over another country
Same as above. Undesirable. Mostly for the same reason. This will impact energy costs/production in Europe. Beyond that, we have to wait and see. One does not want to repeat the mistake of appeasement as with Hitler. However, is it affecting the day to day working and well-being of this nation? Not a bit at the moment. We need to fix ourselves before we start worrying about other nations.
Direct result of money in politics. I don't even know how this is part of your argument. New forays into the business world that can't compete due to carefully crafted legislation given to the congresscritters by their favorite lobbyists. Regulated out of a chance to grow. Plus, politicians siding with moneyed interests rather than trust-busting style leadership where necessary, which would increase competition, drive down costs and increase jobs. Finally, no one dealing with our trade deficits.
Due to loopholes, they aren't high enough.
NSA Spying on American Citizens
What part of military industrial complex do you not understand? There are companies making money off this, lobbying for all the new technology they can bring to bear in this issue, and that is what politicians are concerning themselves with rather than the rights of the people. Another direct result of money in politics.
Mandate? Crafted by insurance companies? Have you read anything about this process?
Veterans Dying at the VA due to negligence
Inexcusable. Absolutely deplorable and inexcusable - but no. Not as big an issue. Terrible, but it does not touch on so many other things at once.
Gun Violence in ethnic neighborhoods
The money of your drug warriors and prison industry lobbyists fuel much of this. The people in those areas make singular mistakes in their lives, usually involving drugs that shouldn't be illegal in the first place, and end up unemployable. How do you stop recidivism? Give people something better to aspire to. If you take that away, nothing stops the downward spiral. The prison complex, particularly for profit private prisons though, love "tough on crime" laws that keep people in jail longer and more likely to come back though.
Special interests paralyzing our legislative process, encouraging government waste, and putting the interest of only the very few above the many touch on every aspect of domestic life today. It won't get better until politicians have to start focusing on the approval of their electorate again, rather than that of certain special interests before they even have the financing to run.