Sen. Jim Talent (R-MO) came out yesterday against a proposed ballot initiative that would protect stem cell research and treatment in Missouri, according to Hotline On Call. His opponent, Claire McCaskill (D), supports the initiative. It’s not yet clear how Talent’s decision will affect his chances of being reelected. “Those who argue that Republicans can't win in Missouri with an unexcited social conservative base will argue that Talent took a step in the right direction as far as re-election is concerned. A Missouri Democrat will argue that the GOP erosion in the suburbs will continue thanks to Talent's decision.” The Kansas City Star notes "Talent’s stand on stem-cell research has taken some confusing twists." [Political Wire]